HORRIDGE, DANIELLEName: Danielle Horridge
Title of Project: 
“Turning on” OipA in cagPAI negative strains of Helicobacter pylori
Advisor: Mark Forsyth
Honors Department: Biology

Helicobacter pylori (HP) is a bacterial pathogen that resides in the stomachs of more than half of the world’s population and has been known to cause ulcers and even gastric cancer. Understanding the mechanisms by which HP can cause this damage is the foundation upon which treatments are created. My project will investigate the relationship between two important virulence factors; the inflammatory protein OipA, and the pathogenicity island CagA in order to learn more about how this relationship aids in host inflammation.

Hometown: Charlottesville, Virginia
Future Plans: 
Hobbies: When I’m not in the lab, I enjoy exploring Colonial Williamsburg with my friends, taking trips to College Creek, cooking, and dabbling in arts and crafts.
Fun Fact: When I was abroad last semester, I played golf (or attempted to at least) on the oldest golf course in the world!


Follow Danielle’s research on the W&M Honors Fellowships blog!